張七鳳博士
姓名 張七鳳博士
現任 研究技師
所屬單位
基因體中心核磁共振核心實驗室 暨 
中央研究院高磁場核磁共振中心

美國俄亥俄州立大學 生物物理 博士, 1997
私立輔仁大學 物理系 學士, 1989
名片
專長

設施管理/專業知識:

本實驗室致力於提供高品質的核磁共振技術支援與研究服務，主要工作如下：
  • 管理實驗室團隊，維護儀器軟硬體之正常運作
  • 協調與分配儀器使用時間，提升使用效率
  • 提供實驗設計與技術操作諮詢
  • 協助圖譜數據之蒐集與分析
  • 培訓新進使用者，指導儀器操作流程
  • 規劃與舉辦相關教育訓練課程
  • 推廣並引進新興核磁共振技術
  • 支援並參與相關研究計畫與合作
 
GRCWeb_CFChang
 
經歷
  • 2010-present 研究技師, 中央研究院基因體中心
  • 2004-2010 副研究技師, 中央研究院基因體中心
  • 2019-present 高磁場核磁共振中心主持人,中央研究院
  • 2002-2018 高磁場核磁共振中心經理,中央研究院
  • 1999-2002 核磁共振實驗室經理, 中央研究院生物醫學科學研究所
  • 1998-2002 兼任助理教授, 輔仁大學物理系
  • 1997-1999 博士後研究,中央研究院生物醫學科學研究所
  • Lin GM, Yu TA, Chang CF, Hsu CH, 2024, “Proline Isomerization and Molten Globular Property of TgPDCD5 Secreted from Toxoplasma gondii Confers Its Regulation of Heparin Sulfate Binding.”, JACS Au, 4(5), 1763-1774. (SCIE, SSCI, A&HCI, Scopus, EI, TSSCI, THCI, Others)
  • Mariasina Sofia S., Chang Chi-Fon, Navalayeu Tsimafei L., Chugunova Anastasia A., Efimov Sergey V., Zgoda Viktor G., Ivlev Vasily A., Dontsova Olga A., Sergiev Petr V., Polshakov Vladimir I.*, 2022, “Williams-Beuren Syndrome Related Methyltransferase WBSCR27: From Structure to Possible Function”, Frontiers in Molecular Biosciences, 9, 865743. (SCIE)
  • Lin MH, Huang YP, Chang CF*, Hsu CH*, 2021, “NMR assignments of the macro domain from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).”, Biomolecular NMR assignments, 15(1), 137-142. (SCIE)
  • Lin MH, Cho CC, Chiu YC, Chien CY, Huang YP, Chang CF, Hsu CH, 2021, “Elucidating the tunability of binding behavior for the MERS-CoV macro domain with NAD metabolites.”, Communications biology, 4(1), 123. (SCIE)
  • Mariasina SS, Chang CF, Petrova OA, Efimov SV, Klochkov VV, Kechko OI, Mitkevich VA, Sergiev PV, Dontsova OA, Polshakov VI, 2020, “Williams-Beuren syndrome-related methyltransferase WBSCR27: cofactor binding and cleavage.”, The FEBS journal, 287(24), 5375-5393. (SCIE)
  • Mariasina SS, Petrova OA, Osterman IA, Sergeeva OV, Efimov SV, Klochkov VV, Sergiev PV, Dontsova OA, Huang TH, Chang CF*, Polshakov VI*, 2018, “NMR assignments of the WBSCR27 protein related to Williams-Beuren syndrome.”, Biomolecular NMR assignments, 12(2), 303-308. (SCIE)
  • Chou CY, Chu M, Chang CF, Yu T, Huang TH, Sakellariou D, 2016, “High sensitivity high-resolution full range relaxometry using a fast mechanical sample shuttling device and a cryo-probe.”, Journal of biomolecular NMR, 66(3), 187-194. (SCIE)
  • Huang YP, Cho CC, Chang CF*, Hsu CH*, 2016, “NMR assignments of the macro domain from Middle East respiratory syndrome coronavirus (MERS-CoV).”, Biomolecular NMR assignments, 10(2), 245-248. (SCIE)
  • Hsu CH, Chang CF, Liao YD, Wu SH, Chen C, 2015, “Solution structure and base specificity of cytotoxic RC-RNase 2 from Rana catesbeiana.”, Archives of biochemistry and biophysics, 584, 70-8. (SCIE)
  • Ming-Yuan Su, Chung-I Chang and Chi-Fon Chang* , 2013, “1H, 13C and 15N resonance assignments of the pyrin domain from human PYNOD ”, Biomolecular NMR Assignments, 7(2), 141-143. (SCIE)
  • Ming-Yuan Su, Chiao-I Kuo, Chi-Fon Chang*, Chung-I Chang*, 2013, “Three-Dimensional Structure of Human NLRP10/PYNOD Pyrin Domain Reveals a Homotypic Interaction Site Distinct from Its Mouse Homologue”, PLoS One, 8(7), e67843. (SCIE)
  • Chou CY, Chu M, Chang CF, Huang TH*, 2012, “A compact high-speed mechanical sample shuttle for field-dependent high-resolution solution NMR.”, Journal of magnetic resonance (San Diego, Calif. : 1997), 214(1), 302-8.