Chi-Fon Chang, Ph.D.
Name Chi-Fon Chang, Ph.D.
現任 Senior Research Specialist/Scientist
所屬單位
GRC NMR Core Facility &
High Field NMR Center, Academia Sinica

Ph.D. Biophysics, The Ohio State University, USA, 1997
B.S., Physics, Fu-Jen Catholic University, Taiwan, 1989
名片
專長

FACILITY MANAGEMENT / EXPERTISE:

My NMR Facilities are dedicated to providing high-quality support and services in NMR related researches. Our main responsibilities include:
  • Managing the core team and ensuring proper maintenance of hardware and software systems
  • Coordinating and scheduling instrument usage to maximize efficiency
  • Offering consultation on experimental design and technical operations
  • Assisting in NMR data acquisition and spectral analysis
  • Training new users in instrument operation and safety procedures
  • Organizing educational and training workshops
  • Promoting and introducing emerging NMR technologies
  • Supporting and participating in related research projects and collaborations
 
GRCWeb_CFChang
 
EDUCATION AND POSITIONS HELD
  • 2010-present Senior Research Specialist, Genomics Research Center, Academia Sinica
  • 2004-2010 Associate Research Specialist, Genomics Research Center, Academia Sinica
  • 2019-present High Field NMR Center, Director & Manager, Academia Sinica
  • 2002-2018 High Field NMR Center, Manager, Academia Sinica
  • 1999-2002 NMR Facility Manager, Institute of Biomedical Sciences, Academia Sinica
  • 1998-2002 Adjunct Assistant Professor, Physics, Fu-Jen Catholic University
  • 1997-1999 Postdoctoral Fellow, Institute of Biomedical Sciences, Academia Sinica
  • Lin GM, Yu TA, Chang CF, Hsu CH, 2024, “Proline Isomerization and Molten Globular Property of TgPDCD5 Secreted from Toxoplasma gondii Confers Its Regulation of Heparin Sulfate Binding.”, JACS Au, 4(5), 1763-1774. (SCIE, SSCI, A&HCI, Scopus, EI, TSSCI, THCI, Others)
  • Mariasina Sofia S., Chang Chi-Fon, Navalayeu Tsimafei L., Chugunova Anastasia A., Efimov Sergey V., Zgoda Viktor G., Ivlev Vasily A., Dontsova Olga A., Sergiev Petr V., Polshakov Vladimir I.*, 2022, “Williams-Beuren Syndrome Related Methyltransferase WBSCR27: From Structure to Possible Function”, Frontiers in Molecular Biosciences, 9, 865743. (SCIE)
  • Lin MH, Huang YP, Chang CF*, Hsu CH*, 2021, “NMR assignments of the macro domain from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).”, Biomolecular NMR assignments, 15(1), 137-142. (SCIE)
  • Lin MH, Cho CC, Chiu YC, Chien CY, Huang YP, Chang CF, Hsu CH, 2021, “Elucidating the tunability of binding behavior for the MERS-CoV macro domain with NAD metabolites.”, Communications biology, 4(1), 123. (SCIE)
  • Mariasina SS, Chang CF, Petrova OA, Efimov SV, Klochkov VV, Kechko OI, Mitkevich VA, Sergiev PV, Dontsova OA, Polshakov VI, 2020, “Williams-Beuren syndrome-related methyltransferase WBSCR27: cofactor binding and cleavage.”, The FEBS journal, 287(24), 5375-5393. (SCIE)
  • Mariasina SS, Petrova OA, Osterman IA, Sergeeva OV, Efimov SV, Klochkov VV, Sergiev PV, Dontsova OA, Huang TH, Chang CF*, Polshakov VI*, 2018, “NMR assignments of the WBSCR27 protein related to Williams-Beuren syndrome.”, Biomolecular NMR assignments, 12(2), 303-308. (SCIE)
  • Chou CY, Chu M, Chang CF, Yu T, Huang TH, Sakellariou D, 2016, “High sensitivity high-resolution full range relaxometry using a fast mechanical sample shuttling device and a cryo-probe.”, Journal of biomolecular NMR, 66(3), 187-194. (SCIE)
  • Huang YP, Cho CC, Chang CF*, Hsu CH*, 2016, “NMR assignments of the macro domain from Middle East respiratory syndrome coronavirus (MERS-CoV).”, Biomolecular NMR assignments, 10(2), 245-248. (SCIE)
  • Hsu CH, Chang CF, Liao YD, Wu SH, Chen C, 2015, “Solution structure and base specificity of cytotoxic RC-RNase 2 from Rana catesbeiana.”, Archives of biochemistry and biophysics, 584, 70-8. (SCIE)
  • Ming-Yuan Su, Chung-I Chang and Chi-Fon Chang* , 2013, “1H, 13C and 15N resonance assignments of the pyrin domain from human PYNOD ”, Biomolecular NMR Assignments, 7(2), 141-143. (SCIE)
  • Ming-Yuan Su, Chiao-I Kuo, Chi-Fon Chang*, Chung-I Chang*, 2013, “Three-Dimensional Structure of Human NLRP10/PYNOD Pyrin Domain Reveals a Homotypic Interaction Site Distinct from Its Mouse Homologue”, PLoS One, 8(7), e67843. (SCIE)
  • Chou CY, Chu M, Chang CF, Huang TH*, 2012, “A compact high-speed mechanical sample shuttle for field-dependent high-resolution solution NMR.”, Journal of magnetic resonance (San Diego, Calif. : 1997), 214(1), 302-8.