mosquito®

This instrument is suitable for microliter protein crystallization screening, supporting sample volumes from 50 nL to 1.2 µL, significantly reducing protein and reagent consumption and improving experimental efficiency. The use of disposable microtips effectively avoids cross-contamination.

Service Fees
One drop per well, 900 NT / plate (96 wells)
Two drops per well, 1,300 NT / plate (96 wells)

Description
One drop : Sample volume limit is 50 nL to 500 nL.
Two drops: Sample volume limit is 50 nL to 150 nL.

Gryphon LCP

LCP is a liquid crystalline phase that forms spontaneously after mixing lipids and water, providing an ideal environment for membrane proteins. The continuous bilayer structure formed by LCP is similar to cell membranes, thus stabilizing proteins and promoting their crystallization.

Note: Users must provide their own consumables. This equipment only provides instrument operation assistance.

Rock Imager®

This automated protein crystal imaging system is specifically designed for crystallization screening, integrating multiple imaging techniques such as visible light and polarized light to present high-resolution crystal observation images. Through timed recording of the crystal growth process, users do not need to manually inspect a large number of crystallization plates, greatly improving efficiency and convenience.

Rigaku MicroMax

This X-ray source is a high-precision instrument specifically used for resolving the structures of protein crystals. It accurately deduces the arrangement of atoms and molecular structure by irradiating protein crystals with high-energy X-rays and measuring the diffraction patterns.

In addition, the X-stream 2000 low-temperature system provides a stable nitrogen gas flow without the need for liquid nitrogen supply, ensuring that crystals maintain their optimal state in a low-temperature environment, improving data quality and experimental efficiency.
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Chameleon®

Chameleon® delivers optimized grid vitrification of biological sample for cryo-electron microscopy (cryo-EM) by combining next-generation automation, blotless grid technology, and high speed plunging. Its core functions include rapid vitrification and automated sample handling, reducing manual operation errors and improving the reproducibility and efficiency of preparation. Through an automated nozzle, samples are precisely sprayed onto specialized grids, and the self-wicking property quickly forms a thin film, effectively solving issues such as the air-water interface and preferred orientation.
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Vitrobot Mark IV

The Vitrobot Mark IV is a semi-automated cryo-electron microscopy sample preparation system specifically designed for vitrification of biological samples. Through adjustable and precise control of temperature, humidity, blot time, and blot force, it enables rapid freezing of samples to prepare optimized vitrified samples. This equipment plays a crucial role in cryo-EM research, significantly improving sample quality and ensuring high-resolution imaging.

Service Fee: 200 NT /Time

Note: Users need to provide their own grids; this equipment only provides filter paper and ethane as consumables.